Understanding PAS and GMS Utility in Dermatopathology

Understanding PAS and GMS Utility in Dermatopathology

Understanding PAS and GMS Utility in Dermatopathology


When it comes to dermatopathology, one of the most crucial aspects is proper diagnosis. A dermatopathology lab that specializes in this field has trained professionals who can accurately identify skin disorders under a microscope. PAS and GMS stainings are two commonly used diagnostic aids in dermatopathology and play a pivotal role in identifying critical microorganisms. In this blog, we will discuss how PAS and GMS utility helps in dermatopathology and how it benefits the patient.


PAS (Periodic acid-Schiff) and GMS (Gomori methenamine-silver) are two commonly used techniques that are used to help diagnose dermatological conditions. PAS is a staining technique that colors fungal cells in purple or magenta and is used in the diagnosis of fungal infections. It works by reacting with the glycogen, mucin, and other neutral polysaccharides present in fungal cell walls. PAS is a part of the routine stainings used in dermatopathology.

GMS, on the other hand, is another widely used stain that helps identify fungi and other microorganisms. GMS stains fungal elements black or dark brown, while other microorganisms are stained gray. GMS is especially useful in diagnosing fungal infections like Pityriasis versicolor, dermatophytosis, onychomycosis, and more.

Apart from fungal infections, PAS and GMS utility can also help diagnose parasitic, viral, and bacterial infections. PAS stain can help identify amebic skin infections and the parasites that cause them, and GMS helps recognize parasitic infections such as histoplasmosis.



Dermatopathology is an essential field when it comes to diagnosing skin disorders. PAS and GMS are two critical diagnostic aids that help dermatopathologists identify the cause of a skin condition to treat it accurately. A dermatopathology lab equipped with highly trained professionals, state-of-the-art tools, and techniques is vital for accurate diagnosis and personalized treatment plans. If you are seeking diagnostic dermatopathology in Pittsburgh PA, contact Rabkin Dermatopathology Lab today for more information on how we can help you with your needs.



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